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Problem-Solving Skills Training for Parents of Children Undergoing Hematopoietic Stem Cell Transplantation: A Mixed

Heather Bemis1,2, Mikela Ritter1, Maxwell Nina Lee1

  • 1Division of Comfort and Palliative Care, Department of Anesthesiology Critical Care Medicine, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA.

Cancers
|March 28, 2025
PubMed

Insights

Bright IDEAS (BI), a problem-solving therapy, showed feasibility and acceptability for caregivers of children undergoing hematopoietic stem cell transplantation (HSCT). BI may reduce caregiver distress, warranting further investigation in a larger trial.

Area of Science:

  • Pediatric Hematology/Oncology
  • Psychological Support Interventions
  • Caregiver Well-being

Background:

  • Caregivers of children undergoing hematopoietic stem cell transplantation (HSCT) experience significant psychological distress.
  • Bright IDEAS (BI), a modified problem-solving therapy, is effective for caregivers of pediatric cancer patients but unstudied in HSCT.
  • This pilot study assessed BI's feasibility, acceptability, and preliminary efficacy in HSCT caregivers.

Purpose of the Study:

  • To evaluate the feasibility and acceptability of the Bright IDEAS (BI) intervention for caregivers of children undergoing HSCT.
  • To examine the preliminary efficacy of BI in reducing psychological distress among these caregivers.
  • To gather qualitative insights into caregiver perceptions of the BI intervention.

Main Methods:

  • A randomized controlled pilot trial comparing BI sessions (6-8 individualized sessions) to usual care.
  • Recruitment of English- and Spanish-speaking caregivers of children (aged 2-21) within 10 days of HSCT.
  • Assessment of psychological distress via self-report measures at baseline and days 60, 90, and 180 post-HSCT; qualitative interviews with a subset of intervention completers.

Main Results:

  • 38 caregivers were enrolled and randomized; 70% of the BI group completed at least six sessions.
  • High completion rates (≥78%) for distress measures were observed across both groups.
  • Caregivers in the BI group showed trends toward lower anxiety and depression scores post-intervention compared to the control group, despite higher baseline distress.

Conclusions:

  • The Bright IDEAS (BI) intervention is feasible and acceptable for caregivers of children undergoing HSCT.
  • Preliminary findings suggest BI may reduce psychological distress in this population.
  • A larger randomized controlled trial is recommended to confirm BI's efficacy in pediatric HSCT caregivers.
Abstract

Keywords:
parent psychological distresspediatric stem cell transplantationproblem-solving skill training

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