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Updated: Jun 29, 2026

Determining Genetic Expression Profiles in C. elegans Using Microarray and Real-time PCR
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Genome-Wide Identification, Gene Duplication, and Expression Pattern of NPC2 Gene Family in Parnassius glacialis

Zhenyao Zhu1, Chengyong Su1, Xuejie Guo1

  • 1College of Life Sciences, Anhui Normal University, Wuhu 241000, China.

Genes
|March 28, 2025
PubMed
Abstract

Keywords:
NPC2 gene familyParnassius glacialisgene duplicationgenome-wide analysistransposable elements

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Occasionally these regions can be adapted to take on new roles within the organism, becoming novel genes...
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Gene Duplication and Divergence

The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
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Exon Recombination

The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
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