Related Experiment Video
Updated: Jun 12, 2026

Real-Time Dynamic Navigation System for the Precise Quad-Zygomatic Implant Placement in a Patient with a Severely Atrophic Maxilla
Published on: October 18, 2021
A Retrospective Study Regarding the Efficacy of Nuvola® OP Clear Aligners in Maxillary Arch Expansion in Adult
Sorana Maria Bucur1, Radu Andrei Moga2, Cristian Doru Olteanu3
1Department of Dentistry, Faculty of Medicine, Dimitrie Cantemir University of Târgu Mureș, 3-5 Bodoni Sandor Street, 540545 Târgu Mureș, Romania.
Abstract:
Background/Objectives: The study evaluated the effectiveness of Nuvola® OP aligners, combined with an interceptive myofunctional device, in achieving dental arch expansions over an 18-26-month treatment period. Methods: 54 patients (31 women and 23 men, aged between 18 and 48 years old) participated in the study. The inclusion criteria for the present research were optimal oral hygiene, no prior orthodontic treatments, and no systemic conditions affecting outcomes of the treatment. Linear measurements (D1, D2, D3, D4) were obtained from STL files of the dental arches before and after treatment using Carestream CSMODEL™ software 3.10.47. Statistical analysis included MANOVA, Pearson's correlation, and paired t-tests, following the Shapiro-Wilk test for data normality. Results: The treatment duration averaged 22.4 months. D1-D4 measurements means increased by 2.1 mm for D1, 2.37 mm for D2, 1.0 mm for D3, and 3.67 mm for D4. MANOVA results (p = 0.063) confirmed similar effects on all parameters, while Pearson's correlation showed a weak positive association among distance changes. Conclusions: Nuvola® OP aligners, used with an interceptive myofunctional device, effectively improved arch parameters. The significant increases in D1-D4 mean values suggest that this approach might be beneficial for controlled dental arch expansion in adult patients.
More Related Videos
Related Concept Videos
Bioavailability Study Design: Single Versus Multiple Dose Studies
Bioavailability Study Design: Healthy Subjects Versus Patients
Bioequivalence studies: Biowaivers
Pharmacodynamics in Geriatric Patients: Effects of Age
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Hypertension III: Clinical Manifestations and Diagnostic Studies

