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Updated: May 7, 2026
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Observation of the Ciliary Movement of Choroid Plexus Epithelial Cells Ex Vivo
Published on: July 13, 2015
Unilateral Reverse Pupillary Block Associated with Multiple Ciliary Body Cysts and Pseudoexfoliative Syndrome.
Idoia Goñi Guarro1,2,3, Mia Zorić Geber1,4, Rašeljka Tadić1,4
1Department of Ophthalmology, University Hospital Centre Sestre Milosrdnice, 10000 Zagreb, Croatia.
Diagnostics (Basel, Switzerland)
|March 28, 2025
Summary
This case highlights bilateral ciliary body cysts causing reverse pupillary block and glaucoma. Surgical intervention successfully lowered intraocular pressure and resolved the block.
Area of Science:
- Ophthalmology
- Glaucoma Research
- Ocular Imaging
Background:
- Pseudoexfoliative syndrome (PEX) is a common cause of secondary glaucoma.
- Ciliary body cysts can cause angle closure, but are often asymptomatic.
- Reverse pupillary block is a less common mechanism for angle closure.
Purpose of the Study:
- To present a unique clinical case of asymmetrical bilateral ciliary body cysts.
- To illustrate their association with pseudoexfoliative syndrome (PEX).
- To detail the development of reverse pupillary block and secondary angle-closure glaucoma.
Main Methods:
- Clinical case presentation with slit lamp examination.
- Multimodal imaging (e.g., ultrasound biomicroscopy, OCT) for cyst and angle assessment.
- Surgical intervention (trabeculectomy) and follow-up.
Main Results:
- Asymmetrical bilateral ciliary body cysts identified, unexpectedly in the contralateral eye.
- Unilateral reverse pupillary block and secondary angle-closure glaucoma in the left eye.
- Successful IOP stabilization and resolution of reverse pupillary block post-trabeculectomy.
Conclusions:
- Ciliary body cysts can contribute to secondary angle-closure glaucoma via iris displacement.
- PEX material and cyst pressure can synergistically cause reverse pupillary block.
- Multimodal imaging is crucial for diagnosing complex glaucoma presentations.
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