Risk-Reducing Gender-Affirming Mastectomy: Unique Considerations in BRCA

Area of Science:

• Oncology
• Gender-affirming care
• Preventative medicine

Background:

• Transmasculine individuals undergoing mastectomy require tailored risk assessments.
• Current guidelines may not fully address breast cancer risk in this population.

Purpose of the Study:

• To advocate for individualized breast cancer risk assessment in transmasculine patients.
• To highlight the benefits of risk-reduction gender-affirming mastectomy.

Main Methods:

• Review of current literature on breast cancer risk in transmasculine individuals.
• Analysis of the role of gender-affirming mastectomy in risk reduction.

Main Results:

• Individualized risk assessment can identify transmasculine patients at higher risk for breast cancer.
• Risk-reduction mastectomy offers a dual benefit of oncologic safety and desired cosmetic results.

Conclusions:

• Integrating personalized breast cancer risk assessment is essential for transmasculine patients.
• This strategy enhances preventative care for an underserved population by offering risk-reduction options.