COVID-19 Infection, Vaccination, and Severe Coronary Artery Disease in Türkiye: A Retrospective Analysis

Esma Çetinkaya1, Ayşe Taş2

  • 1Department of Cardiology, Azienda Ospedaliero-Universitaria Careggi, Florence, Italy.

PubMed

Insights

Neither COVID-19 infection nor vaccination increases long-term cardiovascular disease risk. This study examined coronavirus disease 2019 (COVID-19) vaccine and disease effects on heart conditions in Türkiye.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Immunology

Background:

  • Investigated the impact of COVID-19 infection and vaccination on cardiovascular health in Türkiye, a region with limited prior research.
  • Addressed the potential influence of genetic diversity on disease presentation and treatment outcomes.
  • Focused on patients undergoing angiography to assess heart conditions.

Purpose of the Study:

  • To examine the effects of coronavirus disease 2019 (COVID-19) vaccination and infection on heart conditions in a Turkish patient cohort.
  • To determine if COVID-19 infection or vaccination correlates with the presence or severity of coronary artery disease (CAD).

Main Methods:

  • Included 1935 patients who underwent angiography.
  • Utilized descriptive statistics, including means, standard deviations, numbers, and percentages.
  • Analyzed the relationship between COVID-19 history, vaccination status, and severe CAD.

Main Results:

  • No association was found between prior COVID-19 infection and severe coronary artery disease (CAD).
  • No correlation existed between the time since COVID-19 infection and severe CAD.
  • No significant relationship was observed between the number of mRNA or inactivated vaccine doses and the risk of severe CAD.

Conclusions:

  • Long-term cardiovascular disease risk is not increased by COVID-19 infection or vaccination.
  • The time elapsed since infection or the type of vaccine received did not impact cardiovascular disease risk.
Abstract

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