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Gamma oscillation modulation for cognitive impairment: A systematic review.
Emanuela Bartolini1, Adolfo Di Crosta1, Pasquale La Malva1
1Department of Psychology, University "G. d'Annunzio" of Chieti-Pescara, Chieti, CH, Italy.
Journal of Alzheimer'S Disease : JAD
|March 28, 2025
Summary
Gamma oscillation modulation shows promise for improving cognitive function in Alzheimer's disease (AD) and mild cognitive impairment (MCI). Techniques like transcranial alternating current stimulation (tACS) may enhance memory and overall cognition.
Area of Science:
- Neuroscience
- Cognitive Science
- Gerontology
Background:
- Gamma oscillation modulation is a potential non-invasive treatment for cognitive impairment in Alzheimer's disease (AD) and mild cognitive impairment (MCI).
- Non-invasive brain stimulation (NIBS) techniques, including transcranial alternating current stimulation (tACS), gamma sensory stimulation (GSS), and transcranial magnetic stimulation (TMS), are being explored for cognitive support.
Conclusions:
- Gamma oscillation modulation presents potential cognitive benefits for individuals with AD and MCI, especially for memory enhancement.
- Further research with larger sample sizes and robust study designs is necessary to confirm therapeutic efficacy and optimize intervention parameters.
Keywords:
Alzheimer's diseasecognitive impairmentgamma oscillationmild cognitive impairmentneurostimulationnon-invasive brain stimulation
