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Comparing acute and chronic heart failure patients: the Jordanian Heart Failure Registry (JoHFR)

Hanna Al-Makhamreh1, Kais Al-Balbissi1, Akram Al-Saleh1

  • 1Section of Cardiology, Department of Internal Medicine, Jordan University Hospital, Amman, Jordan.

Minerva Cardiology and Angiology
|March 28, 2025
PubMed

Insights

Acute heart failure (AHF) patients present differently and have worse outcomes than chronic heart failure (CHF) patients, including higher mortality. This comparison highlights key differences in AHF vs. CHF management and prognosis.

Area of Science:

  • Cardiology
  • Clinical Medicine
  • Public Health

Background:

  • Heart failure (HF) is a complex clinical syndrome with distinct chronic and acute presentations.
  • Understanding the differences between acute heart failure (AHF) and chronic heart failure (CHF) is crucial for effective patient management.

Purpose of the Study:

  • To compare acute heart failure (AHF) and chronic heart failure (CHF) patients.
  • To analyze differences in demographics, baseline characteristics, comorbidities, and clinical outcomes between AHF and CHF.

Main Methods:

  • Sub-analysis of the Jordanian HF registry (JoHFR).
  • Involved 2151 HF patients from 21 diverse medical centers.
  • Data collected included demographics, medical history, comorbidities, HF risk factors, and clinical outcomes.

Main Results:

  • AHF patients were more likely to have diabetes and a history of premature atherosclerotic cardiovascular disease (ASCVD).
  • AHF patients showed higher rates of hospital admissions, mechanical ventilation, and mortality compared to CHF patients.
  • Significant differences were observed in gender distribution and family history of premature ASCVD between AHF and CHF groups.

Conclusions:

  • Significant disparities exist in the characteristics and outcomes of AHF versus CHF.
  • Findings from the largest Middle Eastern HF registry provide a basis for improving regional heart failure care.
  • Further research is warranted to enhance heart failure outcomes.
Abstract

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