Related Experiment Video

Updated: Jul 2, 2026

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis
09:52

Histological Quantification to Determine Lung Fungal Burden in Experimental Aspergillosis

Published on: March 9, 2018

Fungal Rhinosinusitis in Cats in the United Kingdom: 34 Cases (2013-2022)

Oliver Luke Russell1,2, Daisy Johnson1,3, Frederik Allan4,5

  • 1Queen's Veterinary School Hospital, University of Cambridge, Cambridge, UK.

Journal of Veterinary Internal Medicine
|March 28, 2025
PubMed
Abstract

Insights

Fungal rhinosinusitis in cats presents with sneezing and nasal discharge, often involving turbinate lysis. Prognosis is guarded, with less than 50% achieving long-term remission after treatment.

Area of Science:

  • Veterinary Medicine
  • Feline Health
  • Infectious Diseases

Background:

  • Fungal rhinosinusitis is an uncommon feline condition in the UK with limited research.
  • Understanding its clinical presentation, diagnosis, and treatment is crucial for feline welfare.

Purpose of the Study:

  • To detail the clinical signs, diagnostic findings, treatments, and outcomes for cats with fungal rhinosinusitis in the UK.
  • To provide insights into the prognosis of this condition in domestic cats.

Main Methods:

  • A retrospective multicenter observational study involving 34 client-owned cats diagnosed with fungal rhinosinusitis.
  • Data collected from 10 UK referral centers between January 2013 and December 2022.

Main Results:

  • Common signs included sneezing (79%) and nasal discharge (62%), with turbinate lysis (79%) and frontal bone osteolysis (47%) frequently observed.
  • Diagnostic tests (culture, PCR, histopathology) showed variable sensitivity; treatment approaches varied, with 26% requiring repeat treatment.
  • Long-term clinical remission (>90 days) was achieved in 38% of cases, with a 9% case fatality rate.

Conclusions:

  • Fungal rhinosinusitis should be considered in cats presenting with nasal disease, regardless of age.
  • The prognosis for feline fungal rhinosinusitis appears guarded, with a significant portion of cats not achieving sustained remission.
Keywords:
aspergilluscryptococcusnasalrhinitissinusitis

More Related Videos

Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic09:03

Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic

Published on: November 7, 2020

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

Related Concept Videos

Urinary Tract Infection I: Introduction01:26

Urinary Tract Infection I: Introduction

Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
The Skin Microbiota01:27

The Skin Microbiota

The human skin serves as a complex ecosystem inhabited by a diverse community of microorganisms, including bacteria, fungi, and viruses. This microbiome plays a critical role in maintaining skin health and defending against pathogenic invaders. The composition of microbial communities varies significantly across different regions of the body, influenced primarily by the local levels of moisture and sebum.Regional Variation in Skin MicrobiotaCutibacterium acnes predominantly colonizes sebaceous...
Microbiome of the Eye01:22

Microbiome of the Eye

The human eye has a specialized microbiota that reflects its unique anatomical and immunological environment. This low-biomass microbial community predominantly colonizes the conjunctiva and eyelid margins, playing a vital role in ocular surface homeostasis and defense. Despite its proximity to the richly colonized facial skin, the ocular surface maintains a distinct microbial profile due to continuous mechanical and biochemical defense mechanisms.The conjunctival surface hosts fewer microbial...
Microbiota of the Respiratory Tract01:29

Microbiota of the Respiratory Tract

The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more like...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...