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Related Concept Videos

Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

96
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
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Appendicitis-II: Diagnostic Studies and Management01:29

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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
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Related Experiment Video

Updated: May 8, 2025

Robot-assisted Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection for Locally Advanced Middle-low Rectal Cancer
12:45

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Early Detection of Local Recurrence After Rectal Cancer Resection in Asymptomatic Patients Is Essential for Survival.

Katharina Esswein1, Eva Hummer1, Marijana Ninkovic1

  • 1Department of Visceral, Transplant, and Thoracic Surgery, Center of Operative Medicine, Medical University of Innsbruck, Innsbruck, Austria.

Journal of Surgical Oncology
|March 28, 2025
PubMed
Summary
This summary is machine-generated.

Early detection of rectal cancer recurrence during follow-up improves outcomes. Achieving R0-resection in local recurrence cases significantly increases overall survival (OS).

Keywords:
R0 resectionprognosisrectal neoplasmsurvivaltreatment outcomes

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Area of Science:

  • Oncology
  • Surgical Oncology
  • Gastrointestinal Cancer Research

Background:

  • Local recurrence after rectal cancer resection presents a significant therapeutic challenge requiring individualized treatment strategies.
  • Management must consider the extent of recurrence and previous treatments.
  • Optimizing outcomes for these patients remains an ongoing clinical concern.

Purpose of the Study:

  • To analyze treatment outcomes for patients experiencing local recurrence after initial rectal cancer resection.
  • To evaluate the rates of R0-resection and overall survival (OS) in this patient cohort.

Main Methods:

  • A retrospective cohort study was conducted.
  • Data from 31 patients with local recurrence following curative resection for rectal cancer between 2003 and 2021 were analyzed.

Main Results:

  • Local recurrence was detected during routine follow-up in 77.4% of cases; 58.1% of patients were symptomatic at diagnosis.
  • Curative treatment was pursued in 48.4% of patients, with 80% achieving R0-resection.
  • Five-year OS was markedly higher for patients with R0-resection (58.3% vs. 5.3%) and lower for symptomatic patients (11.1% vs. 46.2%).

Conclusions:

  • Early detection of rectal cancer recurrence, ideally through scheduled follow-up, is crucial.
  • Achieving complete surgical resection (R0) is a key factor for improved survival in recurrent rectal cancer.