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Updated: May 5, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

How and Why Do Multimorbid Patients Decide to Follow Their Multiple Medication Prescriptions? Looking Beyond the

Juliette Artignan^1,2, Kevin Diter³, Pascal Clerc^4,5

¹Primary Care and Prevention Team, Centre for Research in Epidemiology and Population Health (Inserm U1018), Villejuif, France.

Qualitative Health Research

|March 28, 2025

Summary

This summary is machine-generated.

Multimorbid patients manage multiple medications differently, either deferring to doctors or actively engaging in decision-making. These adherence styles are linked to socioeconomic status, highlighting the need for coordinated care and patient communication.

Keywords:

chronic illness medication adherence multimorbidity patient decision-making polypharmacy socioeconomic status

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Last Updated: May 5, 2026

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Area of Science:

Pharmacology
Health Services Research
Sociology

Background:

Optimizing medication for multimorbid patients is crucial for adherence, safety, and cost-effectiveness.
Patient adherence to complex medication regimens remains poorly understood.
Multimorbidity necessitates careful management of multiple prescriptions.

Purpose of the Study:

To describe how patients account for adherence and non-adherence to multiple medications.
To explore the links between patients' adherence strategies and their socioeconomic status.
To understand patient decision-making processes in managing multiple prescriptions.

Main Methods:

Twenty semi-structured interviews with patients aged 47-82 with cardiovascular disease and chronic conditions.
Analysis using reflexive thematic analysis of transcribed interviews.
Application of Hirschman's theory of voice, exit, and loyalty to interpret findings.

Main Results:

Patients expressed shared concerns regarding multiple medication use and medical uncertainty from conflicting instructions.
Two distinct adherence styles emerged: deferring to physicians versus actively steering decision-making.
These styles correlated with differences in patient-physician engagement, side effect management, and prescription evaluation, and were linked to socioeconomic status.

Conclusions:

Patient adherence strategies vary significantly and are influenced by socioeconomic factors.
Coordinated care is essential to minimize prescription ambiguities for patients with multimorbidity.
Empowering patients with multimorbidity to voice concerns is vital for effective medication management.