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Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
10:27

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts

Published on: July 25, 2020

Aditya Bardia1, Barbara Pistilli1, Hope Rugo1

  • 1Aditya Bardia, MD, MPH, Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, CA, Massachusetts General Hospital Cancer Center, Boston, MA; Barbara Pistilli, MD, Gustave Roussy Cancer Center, Villejuif, France; and Hope Rugo, MD, University of California San Francisco Comprehensive Cancer Center, San Francisco, CA.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
|March 28, 2025
PubMed
Abstract

No abstract available in PubMed .

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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...