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Adult-type granulosa cell tumor with pleural effusion: A rare case report
Minghan Chai1, Qiuli Jin, Jie Zhang
1Department of Gynecology, Shanxian Central Hospital, Heze, Shandong, China.
Rationale:
Adult granulosa cell tumors (AGCTs), representing the most prevalent subtype of sex cord-stromal tumors in the ovary, predominantly manifest in perimenopausal and postmenopausal women. A notably uncommon clinical manifestation of AGCTs is the concomitant development of pleural effusion, a condition that may be erroneously attributed to more prevalent etiologies such as cardiac insufficiency, pulmonary infections, or other malignant processes. Consequently, the occurrence of pleural effusion in association with AGCTs is atypical and warrants heightened clinical vigilance for such rare presentations. This article presents a detailed case report, aiming to enhance the timely identification and management of this condition, thereby optimizing patient prognosis.
Patient Concerns:
A 60-year-old postmenopausal woman presented with a 1-month history of persistent chest tightness and dyspnea. Initial chest radiography demonstrated a right-sided pleural effusion. Thoracentesis was performed, providing transient symptomatic relief; however, the effusion persisted without complete resolution. Further diagnostic evaluation with computed tomography imaging revealed the presence of a pelvic mass, which necessitated surgical intervention for definitive management.
Diagnoses:
Histopathological analysis of the surgical specimen confirmed the diagnosis of an adult granulosa cell tumor originating from the left ovary.
Interventions:
Postoperative evaluation demonstrated a marked reduction in pleural effusion, with complete resolution achieved during the recovery period.
Outcomes:
Throughout the follow-up surveillance, no evidence of tumor recurrence has been detected.
Lessons:
This case highlights the pivotal role of multidisciplinary collaboration in addressing complex clinical scenarios. Furthermore, it emphasizes the imperative for early detection and prompt intervention in cases of pelvic masses among postmenopausal women, underscoring the potential for improved clinical outcomes through timely and coordinated management.
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Clinical Manifestations: