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Cognitive Impairment in IBS: A Narrative Overview.
Himanshi Banker1, Abhishek Goel2, Sunita Kumawat3
1Maulana Azad Medical College, New Delhi, India. himanshiresearch7@gmail.com.
Irritable Bowel Syndrome (IBS) is linked to cognitive dysfunction due to gut-brain axis disturbances. Emerging treatments targeting microbiota, inflammation, and stress show promise for improving IBS-related cognitive symptoms.
Area of Science:
- Gastroenterology
- Neuroscience
- Psychology
Background:
- Irritable Bowel Syndrome (IBS) is a common functional gastrointestinal disorder impacting quality of life.
- Cognitive dysfunction is an emerging, under-recognized symptom in IBS patients.
- The gut-brain axis plays a critical role in IBS pathophysiology.
Purpose of the Study:
- To review the mechanisms linking IBS and cognitive dysfunction.
- To emphasize the role of biological and psychosocial factors in the gut-brain axis.
- To highlight potential treatment strategies for cognitive symptoms in IBS.
Main Methods:
- A comprehensive literature review was performed.
- Searched major medical databases (PubMed, Scopus) for studies from the last decade.
- Focused on clinical and experimental research assessing cognitive impairment in IBS.
Main Results:
- Evidence suggests gut microbiota disturbances, inflammation, neurotransmitter alterations, and psychological stress contribute to cognitive dysfunction in IBS.
- These factors disrupt the gut-brain axis.
- Several treatment modalities show promise.
Conclusions:
- Cognitive dysfunction is a significant issue in IBS patients.
- Increased clinical recognition of these cognitive symptoms is needed.
- Treatments like probiotics, CBT, and pharmaceuticals may alleviate cognitive impairment in IBS.
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