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Congenital anomalies induced in hamster embryos with ribavirin

L Kilham, V H Ferm

    Science (New York, N.Y.)
    |January 28, 1977
    PubMed

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    The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...