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Updated: Jul 5, 2026

Ultra-Fast Amplicon-Based Next-Generation Sequencing in Non-Squamous Non-Small Cell Lung Cancer
Published on: September 8, 2023
[Molecular characterization of lung cancers: up-date and recommendations]
Simon Garinet1, Audrey Mansuet-Lupo2, Diane Damotte2
1Faculté de médecine, université Paris Cité, Paris, France; Unité fonctionnelle d'oncogénétique somatique théranostique et pharmacogénétique, service de biochimie, AP-HP Centre, hôpital européen Georges-Pompidou, Paris, France.
Abstract:
Molecular testing of non-small cell lung cancers has become mandatory at all stages of the disease. National and international recommendations for molecular testing are up-dated regularly. In this review, we will summarize diagnostic approaches focusing on targetable oncogenic alterations (mutations, gene rearrangements) and we will indicate the limits currently associated with sample types and sequencing technologies. Biomarkers that have not showed routine clinical utility will not be presented here.

