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Progression of Paravalvular Leak and Hemolytic Anemia After Implantation of Fifth-Generation Balloon-Expandable
Nozomu Kanehama1, Ryo Ninomiya1, Kengo Tosaka1
1Division of Cardiology, Department of Internal Medicine, Iwate Medical University, Yahaba, Iwate, Japan.
Background:
Progression of paravalvular leak (PVL) and hemolytic anemia are rare complications of newer-generation transcatheter heart valves used for transcatheter aortic valve replacement.
Case Summary:
An 81-year-old man presented with worsening shortness of breath 1 month after implantation of SAPIEN 3 Ultra RESILIA (S3UR). Echocardiography revealed PVL progression and blood tests indicated hemolytic anemia. Percutaneous plug closure was successfully performed, reducing the PVL. His symptoms and hemolytic anemia improved.
Discussion:
The progression of PVL and hemolytic anemia in patients with S3UR has not been previously reported, and their mechanisms require further investigation. Percutaneous plug closure is a good treatment option for PVL after transcatheter aortic valve replacement.
Take-Home Message:
This case demonstrates that PVL progression and hemolytic anemia remain a potential risk after S3UR implantation, which can effectively be treated through percutaneous plug closure.
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