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A Murine Model of Ischemic Retinal Injury Induced by Transient Bilateral Common Carotid Artery Occlusion
Published on: November 12, 2020
From Heart to Eye: Central Retinal Artery Occlusion Secondary to Endocarditis: Septic Embolism
Maria Jose Santa-Ana-Bayona1, Gilberto H Acosta-Gutiérrez1, Pavel Martinez-Dominguez1
1Department of Nuclear Cardiology, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico.
Abstract:
Infective endocarditis (IE) remains a medical challenge. Potential complications such as heart failure and septic embolization may arise, prompting early recognition and treatment. We present the case of a 78-year-old woman with sudden, painless monocular vision loss in the left eye, without other accompanying symptoms. Ophthalmologic evaluation revealed central retinal artery occlusion. A holosystolic murmur was heard at the apex. Further echocardiography confirmed IE. Despite efforts, prognosis of IE is poor, with an in-hospital mortality of 25% in our country, with high risk of embolism (20% to 50%). According to epidemiology, central retinal artery occlusion is a rare complication, resulting from valvular vegetation, occurring in <1% of patients. Unfortunately, there is no accepted treatment to reverse retinal damage caused by central retinal artery occlusion.
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