Association between body roundness index and psoriasis: a cross-sectional study

Area of Science:

• Dermatology
• Public Health
• Obesity Research

Background:

• Psoriasis is a chronic inflammatory disease with complex etiology.
• Abdominal obesity, indicated by the body roundness index (BRI), is a growing public health concern.
• Understanding the link between obesity markers and psoriasis is crucial for prevention and management.

Purpose of the Study:

• To investigate the association between the body roundness index (BRI) and the odds of developing psoriasis.
• To analyze this relationship across diverse ethnic and demographic groups.
• To provide evidence for BRI as a potential risk factor for psoriasis.

Main Methods:

• Cross-sectional analysis of National Health and Nutrition Examination Survey (NHANES) data from 21,242 participants.
• Multivariable weighted logistic regression models to assess BRI and psoriasis odds.
• Restricted cubic spline (RCS) curves for relationship visualization; subgroup and sensitivity analyses performed.

Main Results:

• A significant positive association was found between BRI and psoriasis occurrence.
• Each unit increase in BRI correlated with a 9% increase in psoriasis odds (95% CI: 4%-13%).
• RCS curves and subgroup analyses confirmed a progressive increase in psoriasis odds with higher BRI levels.

Conclusions:

• The body roundness index (BRI) is a significant and reliable predictor of increased psoriasis odds.
• Abdominal obesity, as measured by BRI, may play a role in psoriasis development.
• Findings highlight the importance of monitoring BRI in relation to dermatological health.