Cognitive Level Enhancement through Vision Exams and Refraction (CLEVER): study protocol for a randomised controlled...

Area of Science:

• Ophthalmology
• Gerontology
• Cognitive Science

Background:

• Observational studies link vision impairment to faster cognitive decline.
• No randomized trials have evaluated vision correction's effect on cognitive change.
• A three-year randomized controlled trial protocol is presented to address this gap.

Purpose of the Study:

• To assess the impact of spectacles for distance and/or near vision correction on cognitive change.
• To evaluate spectacles as a low-cost intervention for preventing or delaying cognitive decline in the elderly.
• To provide evidence for public health strategies promoting cognitive health in aging populations.

Main Methods:

• The Cognitive Level Enhancement through Vision Exams and Refraction (CLEVER) trial is a single-center, open-label, randomized controlled trial.
• 760 participants aged ≥60 years with correctable vision impairment and normal cognition will be enrolled.
• The primary outcome is the three-year change in the LASI-DAD global cognitive factor score.

Main Results:

• This section is not applicable as the abstract describes a study protocol, not results.
• The study is designed to collect data on cognitive changes over three years.
• Results will be analyzed to determine the effect of vision correction on cognitive decline.

Conclusions:

• The CLEVER trial is designed to determine if spectacles can prevent or delay cognitive decline.
• Findings could inform interventions aimed at maintaining cognitive function in older adults.
• This research addresses a critical need for evidence-based strategies in geriatric care.