Long-Term Survival Rate for Moroccan Patients with Differentiated Thyroid Cancer
Hajar Tabiti1, Amal Guensi1,2, Karima Bendahhou3
1Laboratory of Cellular and Molecular Inflammatory, Degenerative and Oncologic Pathophysiology, Hassan II University Casablanca, Morocco.
Asian Pacific Journal of Cancer Prevention : APJCP
|March 29, 2025
Summary
This study found that Moroccan patients with differentiated thyroid cancer (DTC) have good survival rates, similar to international data. Key factors like male gender, older age, and tumor characteristics significantly impact long-term outcomes.
Area of Science:
- Endocrinology
- Oncology
- Public Health
Background:
- Differentiated thyroid cancer (DTC) of follicular origin generally has a good prognosis.
- However, overall survival is influenced by various factors.
- This study specifically examines survival rates in Moroccan patients.
Purpose of the Study:
- To analyze five-year and ten-year overall survival rates in follicular differentiated thyroid cancer (DTC).
- To identify independent factors influencing survival in Moroccan patients with DTC.
Main Methods:
- Retrospective cohort study of 1366 patients diagnosed between 2004 and 2012.
- Kaplan-Meier method used to calculate survival rates.
- Log-rank test employed to compare survival based on various factors.
Main Results:
- Five-year survival rate was 94%, and ten-year survival rate was 91%.
- Factors reducing survival include male gender, age >55, tumor size >4 cm, vascular invasion, lymph node invasion, distant metastases, and advanced stage.
- Elevated postoperative thyroglobulin (Tg) and post-radioiodine therapy levels (>10 ng/ml) were also associated with reduced survival.
Conclusions:
- Overall survival rates for Moroccan DTC patients align with international literature.
- Survival is significantly influenced by patient demographics (age, gender), tumor characteristics (histology, size, invasion), and treatment response (Tg levels, RAI therapy).
- Disease stage and risk group are critical determinants of overall survival.
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