Effects of the bread containing resistant starch from wheat (Triticum aestivum) on the improvement in bowel
Yosuke Kikuchi1, Yuto Otomo1, Kazuki Toyota1
1Nisshin Seifun Group Inc., 5-3-1 Tsurugaoka, Fujimino, Saitama, Japan.
Abstract:
This study aimed to evaluate the gut-regulating effects of wheat-derived resistant starch. A randomized, double-blind, placebo-controlled crossover study was conducted with 46 healthy Japanese adults. They were divided into 2 groups, consuming 3.26 g/day of wheat-derived resistant starch and a control food for 4 weeks each, separated by a 4-week washout period. There were no significant differences observed in the primary endpoint of defecation frequency. However, subgroup analysis showed significant improvements in bowel movements for participants who felt a strong sensation of incomplete evacuation. No gut-regulating effects were noted in other subgroups and secondary endpoints. The intake of 3.26 g/day of resistant starch was safe with no overall efficacy observed. Increased stool frequency was observed in participants with less frequent bowel movements and a strong feeling of incomplete evacuation, but no effects were confirmed in other subgroup analyses. No significant changes were observed at secondary endpoints (UMIN ID: UMIN000052543).
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