Pancreatitis-related benign biliary strictures: a review of imaging findings and evolving endoscopic management

Biliary strictures can be secondary to a gamut of etiologies, most of which are malignant and the remaining related to a host of benign causes, including pancreatitis. Pancreatitis related benign biliary strictures (BBS) primarily involve the distal common bile duct (CBD) and can be seen in acute and chronic pancreatitis as well as their other forms, including necrotizing, groove, and autoimmune pancreatitis. Patients with pancreatitis related BBS present along a wide clinical spectrum that spans from an asymptomatic state to biliary obstruction, which not uncommonly facilitates additional workup for malignancy and endoscopic evaluation and treatment. Furthermore, the location and appearance of these strictures lends itself to various imitating benign and malignant etiologies. In this article, we will discuss the pathophysiology and clinicoradiologic features of pancreatitis related BBS while providing a review of an approach to their management focusing on endoscopic techniques.