Association between the preoperative triglyceride-glucose index and myocardial injury following non-cardiac surgery: a cross-sectional study

  • 0Department of Anaesthesiology, Meizhou People's Hospital, Meizhou, Guangdong, China.

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Summary

This summary is machine-generated.

An elevated triglyceride-glucose (TyG) index is linked to myocardial injury after non-cardiac surgery (MINS). Monitoring this index may help manage patients at risk for MINS.

Area Of Science

  • Cardiology
  • Perioperative Medicine
  • Biomarkers

Background

  • The triglyceride-glucose (TyG) index is a marker of insulin resistance.
  • Elevated TyG index is associated with cardiovascular events.
  • The relationship between TyG index and myocardial injury after non-cardiac surgery (MINS) is not well understood.

Purpose Of The Study

  • To investigate the association between preoperative triglyceride-glucose (TyG) index and the incidence of myocardial injury after non-cardiac surgery (MINS).

Main Methods

  • A cross-sectional study was conducted at Meizhou People's Hospital.
  • Adult patients undergoing general anesthesia were included.
  • The preoperative TyG index was calculated using triglyceride and fasting blood glucose levels, and MINS was defined by postoperative troponin measurements.

Main Results

  • The study included 889 patients, with an 8.3% incidence of MINS.
  • The TyG index demonstrated a higher discriminatory ability for MINS compared to triglyceride or fasting blood glucose alone.
  • An elevated preoperative TyG index was independently associated with an increased risk of MINS (OR 1.75, 95% CI 1.21 to 2.52).

Conclusions

  • The preoperative triglyceride-glucose (TyG) index is an independent predictor of myocardial injury after non-cardiac surgery (MINS).
  • Perioperative monitoring of the TyG index could aid in managing patients susceptible to MINS.

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