Geographic Distribution of Racial Differences in Renal Cell Carcinoma Mortality
- Xiaoxian Liu 1, Chengqian Shi 2, Bin Han 1, Jie Yang 2
- Xiaoxian Liu 1, Chengqian Shi 2, Bin Han 1
- 1Department of Nephrology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
- 2Department of Nephrology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
- 0Department of Nephrology, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
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View abstract on PubMed
Summary
This summary is machine-generated.Hispanic patients with Renal Cell Carcinoma (RCC) face higher mortality risks, particularly in specific US regions. Targeted interventions in these areas could reduce RCC survival disparities.
Area Of Science
- Oncology
- Epidemiology
- Health Disparities
Background
- Renal Cell Carcinoma (RCC) survival rates vary among racial and ethnic groups.
- Geographic variations in RCC outcomes and their impact on survival disparities are not well understood.
- Understanding these geographic differences is crucial for addressing healthcare inequities.
Purpose Of The Study
- To investigate geographic disparities in Renal Cell Carcinoma (RCC)-specific death among different racial/ethnic groups.
- To identify specific regions within the US where survival differences are most pronounced.
- To inform targeted interventions aimed at reducing RCC care inequities.
Main Methods
- Retrospective cohort study utilizing data from 2014-2021.
- Data sourced from the Surveillance, Epidemiology, and End Results (SEER) database.
- Analysis focused on RCC-related mortality as the primary outcome.
Main Results
- The study analyzed 85,975 RCC patients across 16 geographic areas.
- Hispanic patients exhibited significantly worse survival outcomes compared to non-Hispanic Whites (HR 1.29).
- Elevated RCC-specific mortality risk for Hispanics was observed in specific regions, including Los Angeles, Greater California, and Atlanta.
Conclusions
- Geographic variations significantly influence RCC survival disparities between Hispanic and non-Hispanic White populations.
- A limited number of geographic regions are associated with substantial population-level differences in RCC survival.
- Implementing targeted interventions in identified high-risk regions can help mitigate national RCC care disparities.
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