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Published on: August 1, 2019
An evaluation of colon cleansing regimens
AJR. American Journal of Roentgenology
|January 1, 1977
Summary
Magnesium citrate and bisacodyl regimens significantly improved colon cleansing quality for barium enema examinations compared to castor oil. Calcium bisdiocytl sulfosuccinate showed no benefit for cleansing but reduced cramping.
Area of Science:
- Gastroenterology
- Radiology
- Clinical Trial Design
Background:
- Effective colon cleansing is crucial for accurate barium enema examinations.
- Various pre-examination regimens exist, but their comparative efficacy requires further investigation.
Purpose of the Study:
- To compare the efficacy of two different colon cleansing regimens.
- To evaluate the impact of specific agents on colon cleansing quality and patient comfort.
Main Methods:
- 500 outpatients were randomized into four colon cleansing regimens.
- Regimens included castor oil or magnesium citrate with bisacodyl, with or without calcium bisdiocytl sulfosuccinate.
- Colon cleansing quality was blindly assessed by three radiologists for 349 patients completing the study.
Main Results:
- Magnesium citrate and bisacodyl regimens were significantly superior to castor oil regimens for colon cleansing quality.
- Calcium bisdiocytl sulfosuccinate did not enhance cleansing quality.
- Calcium bisdiocytl sulfosuccinate appeared to reduce abdominal cramping in patients using magnesium citrate and bisacodyl.
Conclusions:
- Magnesium citrate and bisacodyl represent a more effective colon cleansing regimen for barium enema examinations.
- The study proposes a model for future comparative testing of colon cleansing protocols.
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