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Related Experiment Video

Updated: May 2, 2026

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
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[Artificial intelligence-based fusion prostate biopsy].

Sándor Póth1,2, Róbert Túróczi-Kirizs3, Ágnes Kovács2

  • 11 Szegedi Tudományegyetem, Orvostudományi Kar, Szent-Györgyi Albert Klinikai Központ, Urológiai Klinika Szeged Magyarország.

Orvosi Hetilap
|March 30, 2025
PubMed
Summary
This summary is machine-generated.

Artificial intelligence (AI) and 3D modeling enhance transperineal prostate biopsies, improving cancer detection and significantly reducing infection risk. This AI-assisted fusion biopsy approach offers a safer, more accurate method for diagnosing prostate cancer.

Keywords:
MR fúziós biopsziaMRI fusion biopsyartificial intelligenceinfectologyinfektológiamesterséges intelligenciaprostate cancerprosztatarák

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Area of Science:

  • Urology
  • Medical Imaging
  • Artificial Intelligence in Medicine

Background:

  • Prostate biopsy techniques have evolved from blind sampling to ultrasound-guided and now multiparametric MRI (mpMRI) with fusion biopsy.
  • Accurate detection of clinically significant prostate cancer and minimizing infection risk remain key challenges in prostate biopsy.

Purpose of the Study:

  • To present the initial Hungarian experience with artificial intelligence (AI)-assisted image analysis and 3D virtual modeling in transperineal prostate biopsy.
  • To evaluate the safety, diagnostic accuracy, and efficiency of this novel approach.

Main Methods:

  • Retrospective analysis of 227 transperineal prostate biopsies performed between November 2020 and April 2024.
  • Utilized Watson Elementary® AI for image analysis and PI-RADS v. 2.1 classification, alongside 3D digital modeling.
  • Procedures conducted under anesthesia using the BiopSee® perineal biopsy station.

Main Results:

  • High tumor detection rates: 18% for PI-RADS 3, 72% for PI-RADS 4, and 95.5% for PI-RADS 5.
  • Clinically significant prostate cancer detection rates were 7%, 44%, and 84% for PI-RADS 3, 4, and 5, respectively.
  • Zero infectious complications reported; minimal hematuria/hematospermia (86 cases) and rapid catheter removal (71% within 24 hours).

Conclusions:

  • AI-assisted analysis and 3D modeling in transperineal fusion biopsy provide high patient safety and diagnostic transparency.
  • The transperineal approach, with the institute's protocol, virtually eliminated infection risk.
  • Standardized imaging and sampling protocols can enhance diagnostic and therapeutic decision-making for prostate cancer.