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Acute Pancreatitis II: Clinical Manifestations and Management

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...

Chronic Pancreatitis I: Introduction

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...

Chronic Pancreatitis II: Collaborative Care

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:

Peptic Ulcer Disease V: Surgical Management and Nursing Care

Peptic Ulcer Disease V: Surgical Management and Nursing Care

Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
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Chronic Pancreatitis I: Introduction

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...

Chronic Pancreatitis II: Pathophysiology

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...

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Isolation of Human Islets from Partially Pancreatectomized Patients

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Published on: July 30, 2011

Pancreatic atrophy after gastric cancer surgery: influencing factors and effects on BMI and quality of life.

Zhaoping Li¹, Lianlian Cao¹, Hao Chen²

¹Division of Gastric and Hernia Surgery, Department of General Surgery, Drum Tower Clinical College of Medicine, Nanjing Drum Tower Hospital, Nanjing University of Chinese Medicine, Nanjing, China.

World Journal of Surgical Oncology

|March 30, 2025

Summary

Gastric cancer surgery can lead to pancreatic atrophy, impacting BMI and quality of life. Factors like advanced tumor stage and smoking increase risk, necessitating careful monitoring post-surgery.

Keywords:

Gastrectomy Influencing factor Pancreatic atrophy Quality of life

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Treatment of Middle-segment Pancreatic Benign Tumor Using Laparoscopic Central Pancreatectomy with End-to-end Pancreatic Duct Reconstruction

Treatment of Middle-segment Pancreatic Benign Tumor Using Laparoscopic Central Pancreatectomy with End-to-end Pancreatic Duct Reconstruction

Published on: January 2, 2026

Area of Science:

Gastroenterology
Oncology
Radiology

Background:

Pancreatic atrophy is a known complication after gastric cancer surgery.
Factors influencing pancreatic atrophy and its impact on patient outcomes require further investigation.
Understanding these factors can improve postoperative management for high-risk patients.

Purpose of the Study:

To identify factors contributing to pancreatic atrophy following gastric cancer surgery.
To assess the effects of pancreatic atrophy on body mass index (BMI) and quality of life.
To inform postoperative care strategies for patients at risk of pancreatic atrophy.

Main Methods:

Retrospective analysis of clinical data from 142 gastric cancer patients.
Pancreatic volume measurement using abdominal computed tomography (CT) scans.
Correlation and multiple linear regression analyses to determine influencing factors and relationships.

Main Results:

Significant pancreatic atrophy observed 1 year post-gastric cancer surgery.
Influencing factors identified: T3/T4 tumor stage, low preoperative high-density lipoprotein cholesterol (HDL-C), and smoking history.
Pancreatic atrophy correlated with reduced BMI and poorer quality of life.

Conclusions:

Gastric cancer patients with T3/T4 stages, low preoperative HDL-C, or smoking history require vigilant monitoring.
Close monitoring of pancreatic function, BMI, and quality of life is crucial for these patients.
This study highlights key risk factors for pancreatic atrophy post-gastric cancer surgery.