Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Neutrophilic urticaria.

M S Peters, R K Winkelmann

    The British Journal of Dermatology
    |July 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Histological findings of neutrophil inflammation in dermal venules of urticaria patients may indicate physical urticaria, not early urticarial vasculitis. This suggests a link between specific skin biopsy results and physical urticaria diagnoses.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Segmental type 1 Darier disease: a case series highlighting late-onset disease.

    The British journal of dermatology·2015
    Same author

    Phosphatase and tensin homologue status in sporadic and Cowden syndrome-associated trichilemmomas: evaluation of immunohistochemistry and fluorescence in situ hybridization.

    The British journal of dermatology·2014
    Same author

    Hospitals respond to water loss during the Midwest floods of 1993: preparedness and improvisation.

    The Journal of emergency medicine·1996
    Same author

    Deposition of eosinophil granule proteins precedes blister formation in bullous pemphigoid. Comparison with neutrophil and mast cell granule proteins.

    The American journal of pathology·1996
    Same author

    Kimura's disease and angiolymphoid hyperplasia with eosinophilia: new observations from immunohistochemical studies of lymphocyte markers, endothelial antigens, and granulocyte proteins.

    Journal of cutaneous pathology·1995
    Same author

    Secondary amyloidosis complicating psoriasis.

    Journal of the American Academy of Dermatology·1995
    Same journal

    Improving Prognostication for Cutaneous Squamous Cell Carcinoma.

    The British journal of dermatology·2026
    Same journal

    Recurrent and novel GLTP variants in five patients with nonsyndromic epidermal differentiation disorder: phenotypic and genotypic expansion.

    The British journal of dermatology·2026
    Same journal

    Sustained efficacy of dupilumab in pediatric patients with moderate-to-severe atopic dermatitis over 1 year.

    The British journal of dermatology·2026
    Same journal

    EPHX3-nEDD: from molecular diagnosis to epidermal lipid biology.

    The British journal of dermatology·2026
    Same journal

    BAP1-tumour predisposition syndrome.

    The British journal of dermatology·2026
    Same journal

    Comment on 'Incidence and Mortality of Mucous Membrane Pemphigoid in France': reply from authors.

    The British journal of dermatology·2026
    See all related articles

    Area of Science:

    • Dermatology
    • Pathology
    • Immunology

    Background:

    • Urticaria is a common skin condition characterized by transient, itchy wheals.
    • Urticarial vasculitis is a distinct entity with prolonged lesions and potential systemic involvement.
    • Distinguishing urticarial vasculitis from other forms of urticaria is crucial for appropriate management.

    Purpose of the Study:

    • To investigate the clinical and histological features of urticarial lesions.
    • To determine if specific histological findings in urticaria biopsies correlate with particular subtypes.
    • To differentiate potential early urticarial vasculitis from other urticarial conditions.

    Main Methods:

    • Analysis of 241 consecutive skin biopsies from patients diagnosed with urticaria.

    Related Experiment Videos

  • Histopathological examination of biopsy specimens, focusing on dermal venule inflammation.
  • Review of clinical histories, laboratory data, and immunofluorescence findings for relevant cases.

    • Main Results:

    • Ten out of 241 biopsies (approximately 4.1%) showed inflammation of dermal venules with polymorphonuclear leukocytes.
    • These 10 cases lacked evidence of necrotizing vasculitis.
    • Clinical data revealed associations with dermographism, normocomplementemia, and negative direct immunofluorescence in most of these cases.

    Conclusions:

    • The histological finding of neutrophils in vessel walls within urticarial lesions may suggest physical urticaria.
    • This histological pattern, in the absence of necrotizing vasculitis, is less indicative of early urticarial vasculitis.
    • Clinical correlation, including tests for physical urticaria, is essential when encountering this specific histological presentation.