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Updated: Jul 11, 2026

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Desthiobiotin-Streptavidin-Affinity Mediated Purification of RNA-Interacting Proteins in Mesothelioma Cells
Published on: April 25, 2018
CDKN2A Chromogenic In Situ Hybridization for Separating Benign From Malignant Mesothelial Proliferations
Andrew Churg1,2, Tara Spence1,2, Karina C Martin1,2
1Department of Pathology and Laboratory Medicine, Vancouver General Hospital.
The American Journal of Surgical Pathology
|March 31, 2025
Abstract
None:
CDKN2A FISH is a standard method for separating mesotheliomas from reactive mesothelial proliferations, but FISH requires specialized equipment and technical expertise for interpretation. Here, we show that a commercially available CDKN2A CISH probe provides equivalent information but can be easily scored using an ordinary light microscope and does not require specialized training.

