Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Inborn Errors of Metabolism01:20

Inborn Errors of Metabolism

Phenylketonuria (PKU) is a protein metabolism disorder characterized by high blood levels of the amino acid phenylalanine. This results from a mutation in the gene responsible for phenylalanine hydroxylase, an enzyme that converts phenylalanine into tyrosine. When this enzyme is deficient, phenylalanine builds up in the blood, leading to symptoms such as vomiting, rashes, seizures, growth deficiency, and severe mental retardation. An early diagnosis and a diet restricting phenylalanine intake...
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prevalence of low birth weight and associated factors in Ethiopia: An umbrella review of systematic review and meta-analyses.

PLOS global public health·2025
Same author

Determinants of advanced age pregnancy in Ethiopian; multi-level analysis of Ethiopian demographic health survey 2016.

PloS one·2024
Same author

Reported self-care practice toward prevention of puerperal sepsis and associated factors among postnatal mothers: Community-based cross-sectional study.

SAGE open medicine·2024
Same author

Delay in reaching health facilities for emergency obstetric care and associated factors among postpartum mothers at Bale zones, Ethiopia. A cross-sectional study.

PLOS global public health·2024
Same author

Prevalence and associated risk factors for failed obstetric fistula repair in East African countries: A systematic review and meta-analysis.

SAGE open medicine·2023
Same author

Knowledge of Sexual and Reproductive Health Rights Among University Students: A Cross-Sectional Study in Southeast Ethiopia.

Adolescent health, medicine and therapeutics·2023

Related Experiment Video

Updated: Jul 2, 2026

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
09:04

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas

Published on: September 5, 2011

14.8K

Twin Acardiac: Case Reported From Ethiopia.

Ebisa Erena Muleta1, Girma Geta2, Awel Temema Dube1

  • 1Department of Obstetrics and Gynecology, Goba Referral Hospital Madda Walabu University Goba Oromia Ethiopia.

Clinical Case Reports
|March 31, 2025
PubMed
Summary

Acardiac twinning, a rare condition in identical twin pregnancies, results from abnormal placental blood vessel connections. This case highlights a monochorionic pregnancy with one malformed twin (Twin A) and one healthy twin (Twin B), who sadly passed away shortly after birth.

Keywords:
Ethiopiaacardiaccasetwin

More Related Videos

Implantation of Total Artificial Heart in Congenital Heart Disease
07:27

Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 18, 2014

24.4K
Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
09:51

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

19.5K

Related Experiment Videos

Last Updated: Jul 2, 2026

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
09:04

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas

Published on: September 5, 2011

14.8K
Implantation of Total Artificial Heart in Congenital Heart Disease
07:27

Implantation of Total Artificial Heart in Congenital Heart Disease

Published on: July 18, 2014

24.4K
Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
09:51

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

19.5K

Area of Science:

  • Reproductive Medicine
  • Developmental Biology
  • Medical Genetics

Background:

  • Acardiac twinning is a rare congenital anomaly occurring in monochorionic, monozygotic twin pregnancies.
  • It arises from abnormal placental vascular anastomoses, leading to reversed umbilical artery blood flow to one twin.
  • This condition results in a severely underdeveloped or absent acardiac twin (Twin A) and a typically well-developed pump twin (Twin B).

Purpose of the Study:

  • To report a rare case of acardiac twinning in a monochorionic twin pregnancy.
  • To illustrate the clinical presentation and outcome of this specific congenital anomaly.
  • To contribute to the understanding of vascular anomalies in twin gestations.

Main Methods:

  • Case report of a monochorionic twin pregnancy.
  • Clinical observation and documentation of twin morphology and viability.
  • Postnatal outcome assessment.

Main Results:

  • The pregnancy involved monochorionic twins, designated Twin A and Twin B.
  • Twin A presented as a heterogeneous mass lacking cephalic and cardiac structures, consistent with an acardiac twin.
  • Twin B was morphologically well-formed but tragically demised one week following delivery.

Conclusions:

  • Acardiac twinning represents a severe complication of monochorionic twin pregnancies with significant adverse outcomes.
  • Early recognition and understanding of the pathophysiology are crucial for managing such cases.
  • Despite the pump twin's initial well-being, survival remains precarious, as exemplified by the postnatal demise in this case.