Bilateral breast lymphoma in lactating woman: rare and particularly aggressive entity

Non-Hodgkin's lymphoma (NHL) is seldom encountered in breast. Primary malignant lymphomas of the breast in pregnant or lactating women are more uncommon with massive bilateral breast enlargement rapidly followed by widespread dissemination to several organs. Its diagnosis is often delayed, its treatment still be defined, and its prognosis is particularly poor. We report the case of a 20-year-old Moroccan woman with bilateral primary diffuse B-cell lymphoma of the breast, treated with chemotherapy without a favorable response, progressed to deterioration then death. This case highlights the management difficulties of this group of very high-risk lymphomas.