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Published on: September 22, 2019
Genetic and environmental factors influencing Crohn's disease
Ye-Hui Fan1, Ming-Wei Wang2, Yu-Ning Gao3
1Department of The First Operation Room, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.
Abstract:
This editorial discusses Pellegrino and Gravina's essay. Crohn's disease (CD) is a complex and multifactorial disease that is influenced by a combination of genetic and environmental factors. While genetic factors play a key role in the development of the disease, environmental factors also play a significant role in influencing the risk of developing CD. By looking at present understanding of CD pathogenesis, we emphasize the important factors involved in the development of this illness, such as nucleotide-binding oligomerization domain-2, smoking, and vitamin D. Understanding the interplay between genetic and environmental factors is crucial for developing effective strategies for preventing and treating this chronic inflammatory bowel disease.
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