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Published on: September 26, 2018
Prescribing trends and rational drug use patterns in cardiovascular patients: A cross-sectional observational study
Radhika Chikatipalli1, Anitha Kuttiappan2, Sanjeev Kumar3
1Department of Pharmacology, Sri Venkateswara College of Pharmacy, Chittoor, India.
Insights
Cardiovascular disease (CVD) prescribing trends show frequent use of antiplatelets, diuretics, and hypolipidemics. Opportunities exist to optimize medication management and address polypharmacy in CVD patients.
Area of Science:
- Pharmacology
- Cardiology
- Public Health
Background:
- Cardiovascular diseases (CVDs) are a major global health concern.
- Effective management of CVDs relies on appropriate prescribing practices.
Purpose of the Study:
- To analyze prescribing trends in cardiovascular disease (CVD) patients.
- To assess treatment appropriateness, focusing on guideline adherence, essential medicine use, and generic prescriptions.
Main Methods:
- A cross-sectional observational study was conducted.
- Data on prescribed medications, drug classes, generic prescriptions, and adherence to the Essential Drug List (EDL) were collected and analyzed.
Main Results:
- Antiplatelets, diuretics, and hypolipidemics were the most frequently prescribed drug classes.
- Aspirin, furosemide, amlodipine, and rosuvastatin were commonly prescribed.
- Only 28.8% of prescriptions were generic, and 47.3% of medications were on the EDL.
- An average of 13.2 drugs were prescribed per patient, indicating polypharmacy.
Conclusions:
- Prescribing patterns reveal common drug classes for CVD management.
- There is a need to optimize medication management, including increasing generic drug use and EDL adherence.
- Addressing polypharmacy in CVD patients is crucial for improving treatment outcomes.
Abstract:
Cardiovascular diseases (CVDs), encompassing conditions like coronary artery disease, hypertension and ischemic heart disease, are highly prevalent worldwide. This study analyzed prescribing trends and treatment appropriateness in CVD patients, focusing on adherence to guidelines, essential medicine use and generic drug prescriptions. A cross-sectional observational study was conducted on CVD-diagnosed patients. Data on prescribed medications-including drug classes, generic prescriptions and adherence to the Essential Drug List (EDL)-were collected and analyzed using IBM SPSS version 26.0. The most frequently prescribed drug classes included antiplatelets, diuretics and hypolipidemics. Aspirin was the most commonly prescribed medication (58.1%), followed by furosemide (36.5%), amlodipine (32.4%) and rosuvastatin (24.3%). Statins and calcium channel blockers were prescribed more often than angiotensin II receptor blockers and beta-blockers. On average, 13.2 drugs were prescribed per patient, with only 28.8% prescribed generically. Furthermore, 47.3% of medications were on the EDL. This study highlights the high prevalence of CVDs and the common drug classes prescribed to manage them. These findings provide important insights into current prescribing trends, particularly the frequent use of anti-hypertensive, antiplatelets, diuretics and hypolipidemics and suggest areas for optimizing medication management in this population. Additionally, there is a need to better manage polypharmacy in CVD patients.
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