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Updated: Aug 18, 2026

Videomorphometric Analysis of Hypoxic Pulmonary Vasoconstriction of Intra-pulmonary Arteries Using Murine Precision Cut Lung Slices
Published on: January 14, 2014
[Comparative morphofunctional research on the individual resistance of animals to hypoxia]
Abstract:
It has been shown in experiments on white male rats that there is a correlation between hypoxia tolerance and the rate of metabolism in brain tissue. Animals with varying tolerance to hypoxia differed also in the acid-base balance of venous blood outflowing from the brain. While adapting to hypoxia animals with high individual tolerance developed the main metabolic changes in the reticular formation and those with low tolerance in the cerebral cortex. During adaptation to hypoxia animals with high and low tolerance had varying changes in acid-base balance. The data obtained allow the conclusion that there is a correlation between the rate of brain tissue metabolism, acid-base balance of jugular vein blood and individual animals' tolerance to hypoxia.

