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Gender Differences in Predicting Metabolic Syndrome Among Hospital Employees Using Machine Learning Models: A

Yi-Syuan Wu1, Wen-Chii Tzeng2, Cheng-Wei Wu3

  • 1Department of Computer Science and Information Engineering, National Taitung University, Taitung, Taiwan.

The Journal of Nursing Research : JNR
|March 31, 2025
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Summary
This summary is machine-generated.

Machine learning accurately predicts metabolic syndrome (MetS) in hospital employees. The Naïve Bayes model, considering gender differences, improves early risk identification for better cardiovascular health outcomes.

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Area of Science:

  • Health Informatics
  • Machine Learning in Healthcare
  • Preventive Cardiology

Background:

  • Metabolic syndrome (MetS) is a cluster of conditions including obesity, high blood glucose, dyslipidemia, and hypertension.
  • Early prediction of MetS risk, especially considering gender-specific factors, can improve cardiovascular health outcomes in hospital employees.

Purpose of the Study:

  • To develop and optimize a machine learning model for predicting MetS risk in hospital employees.
  • To investigate gender-specific differences in MetS prediction.

Main Methods:

  • A population-based survey of 3,537 hospital employees (aged 20-65) from 2018-2020.
  • Data included demographics, anthropometrics, medical history, lifestyle, and biochemical markers.
  • Six machine learning models (K-NN, Random Forest, Logistic Regression, SVM, Neural Network, Naïve Bayes) were employed and evaluated.

Main Results:

  • MetS prevalence was 8.91%.
  • The Naïve Bayes model demonstrated superior performance (sensitivity 0.825, accuracy 0.859, AUC 0.936).
  • Key predictors included BMI and ALT (both genders), with gender-specific factors like age, uric acid, AST (men), and chronic disease, phosphorus (women).

Conclusions:

  • The Naïve Bayes model is effective for gender-independent MetS prediction in hospital employees.
  • Integrating gender-specific factors into MetS prediction models is crucial for routine health screening and cardiovascular disease prevention.