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Venous thrombectomy: Device landscape and applications
Benjamin Ogbonna1, Eric Monroe2, David Shin3
1Department of Biomedical Engineering, Johns Hopkins University, 3400 N. Charles Street, Baltimore, USA.
Abstract:
Percutaneous mechanical thrombectomy (PMT) has emerged as a prominent treatment option for venous thromboembolism, offering advantages over catheter-directed thrombolysis and anticoagulation therapy, such as reduced bleeding risk and faster thrombus resolution. PMT devices operate through three main mechanisms: aspiration to directly extract thrombi, mechanical fragmentation to break thrombi into smaller pieces, and rheolytic disruption using high-pressure saline jets to dislodge and remove thrombi. This review summarizes the modern PMT device landscape, technical specifications, and indications while exploring extended and off-label uses and highlighting its expanding clinical applications.
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