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Updated: Jun 7, 2026
A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Midterm Outcomes of the Fenestrated Anaconda Stent Graft for Complex Aortic Aneurysm Repair: A Large, Single Centre,
Marine Bordet1, Mohammed Alkhani2, Nellie Della-Schiava1
1Department of Vascular and Endovascular Surgery, Hospices Civils de Lyon, Louis Pradel University Hospital, Bron, France; Université de Lyon, INSA-Lyon, LGEF, EA682, Villeurbanne, France.
Objective:
The aim of this study was to evaluate the short and midterm outcomes of the Anaconda fenestrated stent graft for the treatment of complex abdominal and thoraco-abdominal aneurysms.
Methods:
This was a retrospective study in a single academic centre. All patients treated consecutively with a fenestrated Anaconda device between January 2019 and May 2024 were included. Outcomes analysed included technical success (TS), procedure related death, occurrence of major adverse events (MAEs) and target vessel instability (TVI), type Ia endoleak (T1aEL), abdominal aortic aneurysm (AAA) related re-interventions, sac changes, and death.
Results:
Two hundred and ten patients were treated with the Anaconda stent graft. The mean AAA diameter was 60.4 ± 9.4 mm, with a mean of 3.9 ± 0.6 fenestrations per patient for a total of 816 target vessels (TVs). TS was 96.2% (202/210), MAEs occurred in 6.2% of patients (13/210), and procedure related death was 2.9% (6/210). The mean follow up was 24.0 ± 18.3 months. AAA related re-intervention was necessary in 18.6% of patients. Primary and secondary TV patency at follow up were 97.1% (8792/816) and 98.0% (800/816), respectively Freedom from TVI at one, three, and five years was 95.5% (95% confidence interval [CI] 93.9 - 97.1%), 92.5% (95% CI 90.2 - 94.8%), and 91.7% (95% CI 89.0 - 94.4%), respectively. No T1aELs were observed during follow up. Estimated freedom from sac enlargement at one, three, and four years was 96.9% (95% CI 94.3 - 99.6%), 88.4% (95% CI 82.6 - 94.3%), and 82.8% (95% CI 74.1 - 91.6%), respectively. Estimated overall survival at one, three, and five years was 92.2% (95% CI 88.6 - 95.9%), 80.0% (95% CI 73.3 - 86.8%), and 71.6% (95% CI 62.1 - 81.0%), respectively, with one case (0.5%) of late aortic related death.
Conclusion:
Endovascular repair of complex abdominal or thoraco-abdominal aneurysms using the fenestrated Anaconda stent graft is safe and effective with a high TS and low procedure related mortality rate. The midterm results appear satisfactory in terms of sac evolution, with a low TVI rate. The need for re-intervention is acceptable and justifies the need for meticulous imaging follow up.
