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Updated: May 16, 2025

Biodegradable Magnesium Stent Treatment of Saccular Aneurysms in a Rat Model - Introduction of the Surgical Technique
Published on: October 1, 2017
Structural Design of Biodegradable Mg Gastrointestinal Anastomosis Staples for Corrosion and Mechanical Strength
Lin Mao1, Xue Cai1, Zhongxin Hu1
1School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 20093, China.
Abstract:
Magnesium (Mg) and its alloys, as next-generation materials for anastomosis staples, offer promising advantages such as biodegradability, biocompatibility, and reduced risk of long-term complications compared to traditional titanium materials. However, the performance of biodegradable staples is highly dependent on their structure. In this study, a biodegradable high-purity (HP) Mg staple with an optimized structure intended for small intestine anastomosis was developed and evaluated in vitro. The designed staple, with a diameter of 0.3 mm, featured an interior angle of 100° and a height of 3.8 mm. This design exhibited a maximum effective stress of approximately 170 MPa and an effective strain of 1.63. The staple could maintain structural integrity without fracture after 7 days of in vitro corrosion testing and exhibited a relatively high burst pressure of approximately 54.70 ± 2.51 mmHg. These findings indicate that the newly designed HP Mg staple combines superior corrosion resistance and anastomosis strength, confirming its potential for clinical application.
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