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A silence catalyst: CCL5-mediated intercellular communication in cancer

Wei-Ting Hu1, Ming Li2, Pei-Jun Ma1

  • 1Department of Clinical Pharmacology, School of Pharmacy, China Medical University, No.77 Puhe Road, Shenyang North New Area, Shenyang, 110122, Liaoning, China.

Archives of Toxicology
|April 1, 2025
PubMed
Summary

Chemokine CCL5 (RANTES) is crucial in cancer, influencing tumor growth, metastasis, and immune evasion. This review details its role in the tumor microenvironment and intercellular communication, offering potential diagnostic and therapeutic targets.

Keywords:
CCL5CancerIntercellular communicationReceptorTumor microenvironment

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