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Switching Conjugation Is the Predominant Factor Contributing to Complete Reversal of Amide cis-trans (Z-E) Preference

Junjun Huang1,2, Luying Chen3,2, Hirotaka Ikeda2

  • 1The Fifth Affiliated Hospital, Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, The NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou 511436, China.

The Journal of Organic Chemistry
|April 1, 2025
PubMed

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