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Published on: August 24, 2015
The relationship between platelet parameters and bacterial types in patients with bacteremia: A retrospective
Xiaoyan Liu1, Guanqun Yi2, Guoyang Zhang1
1Department of Hematology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China.
Objective:
To analyze the relationship between platelet parameters and bacterial types in patients with bacteremia.
Methodology:
Data from 265 patients with positive blood bacterial cultures were collected. Clinical parameters and procalcitonin (PCT) were recorded.
Results:
In 265 patients with bacteremia, gram-negative (G-) bacteria accounted for 56% of cases, and gram-positive (G +) bacteria accounted for 44% of cases. In patients with bacteremia, white blood cell counts (WBC), neutrophil counts (NEUT), the percentage of neutrophils (NEUT%), and PCT were increased, and lymphocyte counts (LYM) and the percentage of lymphocytes (LYM%) were decreased. The differences in plateletcrit values, NEUT%, LYM%, and PCT between the G- and the G + bacteria group were significantly different. The cutoff values of PCT, platelet, plateletcrit, and NEUT% were 1.31 ng/mL, 211 × 109/L, 0.205%, and 87.41%, respectively. The incidence of thrombocytopenia was 12%. There was no significant difference in WBC, NEUT%, PCT, platelet, platelet nadir, and days of thrombocytopenia between the G- and the G + bacteria among patients with thrombocytopenia.
Conclusions:
Platelet, plateletcrit, NEUT%, and PCT are helpful for the early identification of G- and G + bacteria. The combination of PCT and hemogram parameters is more conducive to the early differential diagnosis of bacterial classification.
