Related Experiment Video
Updated: Aug 3, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
Published on: August 28, 2018
[Calcification in the heart. I. Spontaneous coronary embolism due to calcified material]
Insights
Calcific emboli were found in 45% of hearts with severe calcified heart valves. These emboli, particularly in the coronary arteries, are linked to mitral valve disease and ischemic heart symptoms.
Area of Science:
- Cardiology
- Radiology
- Pathology
Context:
- Advanced calcification of left heart valves is a common finding in cardiovascular disease.
- The presence and significance of spontaneous "calcific" emboli in this context are not fully understood.
Purpose:
- To investigate the occurrence and characteristics of spontaneous "calcific" emboli in hearts with advanced valvular calcification.
- To determine the association between valvular calcification, emboli formation, and ischemic heart disease.
Summary:
- X-ray imaging revealed coronary emboli in 45% (14 out of 31) of hearts with severe left heart valve calcification.
- A total of 265 "calcific" emboli were identified, with 205 within coronary arteries and 60 in the left ventricular cavity.
- Embolization was most frequent and extensive in cases of postrheumatic mitral valve disease.
Impact:
- Findings suggest that coronary "calcific" embolization should be considered in the differential diagnosis of ischemic heart disease symptoms in patients with valvular heart lesions.
- This study highlights a potential link between valvular calcification and embolic events, impacting patient management and diagnostic approaches.
Abstract:
Thirty-one hearts with advanced calcification of one or both left heart valves were investigated for the presence of spontaneous "calcific" emboli. X-ray (mammography) showed coronary emboli in 14 cases, that is in 45% of the whole series. A total of 265 "calcific" emboli (205 intracoronary and 60 in the left ventricular cavity) was demonstrated. The embolisation occurred most frequently and most extensively in association with postrheumatic mitral valve disease. Coronary "calcific" embolisation must be considered in the differential diagnosis of symptoms of ischemic heart disease in patients suffering from valvular heart lesions.
More Related Videos
11:30A Semi-Automated and Reproducible Biological-Based Method to Quantify Calcium Deposition In Vitro
Published on: June 2, 2022
06:57Semi-Automatic Graphical Tool for Measuring Coronary Artery Spatially Weighted Calcium Score from Gated Cardiac Computed Tomography Images
Published on: September 22, 2023
Related Concept Videos
Imaging Studies for Cardiovascular System III: X-Ray
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Coronary Artery Disease II: Pathophysiology
Coronary Artery Disease III: Clinical Manifestations
Acute Coronary Syndrome I: Introduction
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations