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Updated: Jun 27, 2026

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In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears
Published on: February 21, 2018
Vestibular function in probable versus definite Ménière's disease: a cross-sectional retrospective analysis
Oğulcan Gündoğdu1, Cem Yeral2, Ayberk Aydın Tunc2
1Department of Audiology, Institute of Health Sciences, Istanbul University-Cerrahpasa, Istanbul, Turkey.
The Journal of Laryngology and Otology
|April 2, 2025
Summary
Vestibular evoked myogenic potentials (VEMPs) show promise in differentiating probable and definite Ménière
Area of Science:
- Neurology
- Otolaryngology
- Vestibular Science
Background:
- Ménière's disease is an inner-ear disorder characterized by endolymphatic hydrops.
- It presents with recurrent vertigo, fluctuating hearing loss, and tinnitus.
- Ménière's disease is classified as 'probable' or 'definite' based on Bárány Society criteria.
Purpose of the Study:
- To evaluate the utility of vestibular evoked myogenic potentials (VEMPs) in distinguishing between probable and definite Ménière's disease.
- To assess vestibular function using ocular-VEMPs (oVEMPs), cervical-VEMPs (cVEMPs), and caloric testing.
Main Methods:
- Analytical cross-sectional retrospective study.
- Inclusion of 28 Ménière's disease patients (15 definite, 13 probable).
- Assessment of vestibular function via oVEMPs, cVEMPs, and caloric testing.
Main Results:
- Significant differences in VEMP asymmetry rates were found between the probable and definite Ménière's disease groups.
- The definite Ménière's disease group showed a higher incidence of abnormal VEMP responses.
- Vestibular evoked myogenic potentials testing demonstrated potential for differentiating Ménière's disease subtypes.
Conclusions:
- Vestibular evoked myogenic potentials may serve as a valuable diagnostic tool for differentiating probable and definite Ménière's disease.
- Further research is warranted to validate these findings and guide clinical applications.
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