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Updated: May 16, 2025

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Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
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Characterizing Disparities in Access to Surgery for Pituitary Adenomas: A National Cancer Database Analysis
Miguel Angel Jimenez1,2, Melanie A Horowitz2, Julian L Gendreau2
1Department of Neurological Surgery, The University of Chicago Pritzker School of Medicine, Chicago, IL 60637, USA.
The Journal of Clinical Endocrinology and Metabolism
|April 2, 2025
Summary
Racial and socioeconomic factors significantly limit access to high-volume facilities for pituitary adenoma surgery. Addressing these disparities is crucial for equitable patient outcomes in neurosurgery.
Area of Science:
- Neurosurgery
- Health Services Research
- Health Equity
Background:
- High-volume facilities (HVFs) offer improved postoperative outcomes for pituitary adenomas (PA).
- Equitable access to these specialized centers remains a significant challenge.
- Understanding disparities in access is critical for improving patient care.
Purpose of the Study:
- To investigate racial and socioeconomic disparities in access to HVFs for PA surgery in the United States.
- To identify factors contributing to unequal distribution of PA patients at HVFs.
- To inform strategies for enhancing equitable access to specialized neurosurgical care.
Main Methods:
- Retrospective analysis of 57,807 adult patients with PA from the National Cancer Database (NCDB), 2004-2019.
- Evaluation of baseline patient characteristics, surgical site, and survival outcomes.
- Multivariable analysis to identify predictors of accessing HVFs for PA resection.
Main Results:
- Nearly half (47.6%) of PA patients underwent surgery at a HVF.
- African-American and Hispanic patients had significantly lower odds of surgery at HVFs.
- Lower income, Medicaid insurance, rural location, and lower educational attainment were associated with reduced HVF access.
- An increasing trend in HVF access for PA patients was observed over time.
Conclusions:
- Significant racial and socioeconomic disparities exist in accessing HVFs for pituitary adenoma surgery.
- These disparities impact equitable distribution of care for PA patients.
- Targeted interventions are needed to address these access barriers and promote health equity.

