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Updated: Jun 30, 2026

Implantation of the Syncardia Total Artificial Heart
Published on: July 18, 2014
Case report: morphological challenges to surgical repair in complete atrioventricular septal defect with isolated
Martina Larsson1, Mats Synnergren2, Thushara Rodrigo1
1Department of Paediatric Cardiology, Great Ormond Street Hospital, London, UK.
Abstract:
We describe a trisomy 21 patient with postnatal diagnosis of atrioventricular septal defect with isolated ventricular component who had a complicated post-surgical course following complete repair. Clinical outcomes included moderate-severe residual atrioventricular valve regurgitation needing re-operation, complete heart block leading to pacemaker insertion, seizures secondary to subdural haemorrhages, and chylothorax. We describe the surgical considerations specific to this cardiac morphology.
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