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Related Concept Videos

Preclinical Development: Overview01:28

Preclinical Development: Overview

Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
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The three-compartment open model is a pharmacokinetic model used to describe the distribution and elimination of drugs following extravascular administration. It comprises a central compartment representing the plasma and two peripheral compartments. The highly perfused peripheral compartment represents organs and tissues with a rich blood supply, such as the liver, kidneys, and lungs. The scarcely perfused peripheral compartment represents tissues with lower blood supply, such as adipose...

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An In Vitro Dissolution Determination of Multi-Index Components in Tibetan Medicine Rhodiola Granules
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Corrigendum: Development and validation a methodology model for traditional Chinese medicine good practice

Su Li1,2,3, Luan Zhang4, Yangyang Wang1,3

  • 1The Second Clinical College, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.

Frontiers in Pharmacology
|April 2, 2025
PubMed
Summary

This study corrects a previously published article DOI. The correction ensures accurate referencing for future scientific research and data integrity.

Area of Science:

  • Scientific publishing
  • Scholarly communication
  • Research integrity
Keywords:
good practice recommendation (GPR)guidelinesmethodology modelmixed methodtraditional chinese medicine (TCM)

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