Correlation between cardiometabolic index and psoriasis: a cross-sectional analysis using NHANES data

Area of Science:

• Cardiology
• Dermatology
• Metabolic Health

Background:

• Psoriasis is a chronic inflammatory skin condition with known links to metabolic health issues.
• The Cardiometabolic Index (CMI) offers a straightforward method to evaluate overall cardiometabolic health.
• Understanding the relationship between CMI and psoriasis is crucial for comprehensive patient care.

Purpose of the Study:

• To investigate the association between the Cardiometabolic Index (CMI) and the prevalence of psoriasis.
• To determine if CMI can serve as a predictive marker for psoriasis risk.
• To explore the linear relationship between CMI and psoriasis in a large adult population.

Main Methods:

• Utilized data from the National Health and Nutrition Examination Survey (NHANES) from 2003-2014.
• Included 7,327 American adults with self-reported psoriasis diagnoses and data for CMI calculation.
• Employed multivariable logistic regression and smooth curve fitting to analyze the CMI-psoriasis relationship.

Main Results:

• A significant linear correlation was observed between CMI and psoriasis (P < 0.05).
• Individuals with the highest CMI had a 71% increased probability of psoriasis compared to those with the lowest CMI (OR = 1.71).
• Subgroup analyses did not reveal significant interactions, indicating a consistent association across demographics.

Conclusions:

• A substantial linear relationship exists between CMI and psoriasis in American adults.
• Elevated CMI is associated with a higher likelihood of developing psoriasis.
• This research supports using CMI for identifying individuals at risk, informing public health strategies and therapeutic interventions.