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Published on: November 5, 2019
Corynebacterium striatum-Induced Meningitis in a Non-immunocompromised Patient
Tamar Megrelishvili1, Elene Saribekovi2, Elene Pachkoria1
1Department of Infectious Diseases, First University Clinic of Tbilisi State Medical University, Tbilisi, GEO.
Abstract:
We present the case of a 46-year-old immunocompetent male diagnosed with meningitis caused by Corynebacterium striatum, a rare pathogen typically found in immunocompromised individuals. The diagnosis was confirmed by cerebrospinal fluid (CSF) culture, which grew C. striatum, and was supported by the exclusion of other common pathogens causing meningitis, including viral etiology, using polymerase chain reaction (PCR) testing. This case highlights the potential of C. striatum to cause central nervous system (CNS) infections in otherwise healthy individuals. The patient had a history of prosthetic hip joint placement, which may have served as a potential source of infection. After appropriate antibiotic therapy with vancomycin and amikacin, the patient fully recovered. This case underscores the importance of considering uncommon pathogens in the differential diagnosis of meningitis, even in patients without traditional risk factors.
Insights
A rare meningitis case in an immunocompetent man caused by Corynebacterium striatum highlights the need to consider uncommon pathogens. Prompt diagnosis and antibiotic treatment led to full recovery.
Area of Science:
- Infectious Diseases
- Neurology
- Microbiology
Background:
- Corynebacterium striatum is an unusual cause of meningitis, typically seen in immunocompromised patients.
- Central nervous system (CNS) infections require prompt diagnosis and management to prevent severe outcomes.
- Identifying the causative pathogen is crucial for effective antimicrobial therapy.

