Nonpharmacologic interventions to improve quality of life of older adults with HIV

Ensuring optimal quality of life (QOL) in older adults with HIV (OAWH) should be a priority. Comprehensive strategies are needed not only to assess QOL but also to implement targeted interventions that enhance it across multiple dimensions. This review aims to examine the robust scientific evidence supporting the effectiveness of nonpharmacological interventions, such as exercise, socialization, and psychological support.

Physical activity and structured exercise programs have been shown to improve functional capacity, reduce frailty, alleviate depressive symptoms, and enhance psychological well being in OAWH. Studies indicate that interventions such as home-based exercise programs, community-based support, and digital health initiatives can help mitigate isolation, reduce depressive symptoms, and improve socialization.

There remains a gap between the scientific evidence demonstrating the benefits of nonpharmacological interventions and their implementation in clinical practice. A shift from disease-centered to person-centered medicine is necessary to adequately address the real needs of OAWH. From a healthcare policy perspective, a fundamental change in approach is essential, with greater investment in evidence-based strategies - such as exercise, socialization, and psychological support - even if it requires rethinking the current care model.